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David M Virshup Selected Research

Wnt Proteins

1/2021Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling.
1/2021A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.
3/2015Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression.

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David M Virshup Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 04/2005
4Breast Neoplasms (Breast Cancer)
11/2016 - 01/2013
3Carcinogenesis
01/2019 - 01/2012
2Stomach Neoplasms (Stomach Cancer)
01/2021 - 03/2015
2Fibrosis (Cirrhosis)
12/2019 - 05/2016
2Ureteral Obstruction
12/2019 - 05/2016
2Genetic Translocation (Chromosomal Translocation)
05/2016 - 09/2002
2Leukemia
10/2015 - 08/2015
2Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
03/2007 - 02/2002
1Focal Dermal Hypoplasia (Syndrome, Goltz)
12/2021
1Coloboma (Colobomas)
01/2021
1Hereditary renal agenesis
01/2021
1Syndactyly (Polysyndactyly)
01/2021
1Microcephaly
01/2021
1Alopecia (Baldness)
01/2021
1Fanconi Anemia (Fanconi's Anemia)
01/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
10/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Glioma (Gliomas)
01/2019
1Teratoma (Teratoid Tumor)
10/2016
1Fasciitis (Fascitis)
05/2016
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2015
1Blast Crisis (Blast Phase)
10/2015
1Cholangiocarcinoma
03/2015
1Carcinoma (Carcinomatosis)
03/2015
1Astrocytoma (Pilocytic Astrocytoma)
03/2015
1Radiation Injuries (Radiation Sickness)
06/2014
1Chromosomal Instability (Chromosome Stability)
05/2013
1Fibrosarcoma
10/2012
1Inflammation (Inflammations)
10/2010
1Pathologic Processes
07/2008
1Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)
03/2007
1Adenomatous Polyps
03/2007
1Colonic Neoplasms (Colon Cancer)
03/2007
1Adenoma (Adenomas)
03/2007
1Acrocephalosyndactylia (Apert Syndrome)
04/2005
1Neuroblastoma
11/2002

Drug/Important Bio-Agent (IBA)

13CateninsIBA
01/2021 - 10/2010
8Proteins (Proteins, Gene)FDA Link
05/2016 - 09/2002
5LigandsIBA
01/2021 - 07/2008
4Phosphotransferases (Kinase)IBA
01/2022 - 11/2002
3EnzymesIBA
01/2022 - 05/2016
3Wnt ProteinsIBA
01/2021 - 03/2015
3Wnt ReceptorsIBA
01/2020 - 05/2015
3Protein Isoforms (Isoforms)IBA
12/2019 - 05/2016
2Serine (L-Serine)FDA Link
12/2021 - 04/2005
2AcyltransferasesIBA
12/2021 - 01/2013
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 03/2007
2UbiquitinIBA
12/2020 - 05/2016
2Ligases (Synthetase)IBA
12/2020 - 05/2016
2ETC-159IBA
12/2019 - 10/2019
2Biomarkers (Surrogate Marker)IBA
03/2016 - 03/2015
2beta CateninIBA
03/2007 - 02/2002
1CholesterolIBA
01/2022
1A-factor (Streptomyces)IBA
01/2022
1palmitoleic acidIBA
12/2021
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2021
1olaparibIBA
01/2021
1Long Noncoding RNAIBA
10/2020
1CollagenIBA
12/2019
1RNA IsoformsIBA
12/2019
1RNA (Ribonucleic Acid)IBA
12/2019
1TransferasesIBA
12/2019
12- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA
10/2019
1AgarIBA
10/2019
1Small Interfering RNA (siRNA)IBA
01/2019
1Neurofibromin 1 (Neurofibromin)IBA
01/2019
1Leucine (L-Leucine)FDA Link
01/2019
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1Transcription Factors (Transcription Factor)IBA
11/2016
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2016
1Telomerase (Telomerase Reverse Transcriptase)IBA
10/2016
1ZincIBA
05/2016
1Lipoproteins (Lipoprotein)IBA
05/2016
1Casein Kinase I (Casein Kinase 1)IBA
05/2016
1CytokinesIBA
05/2016
1Dasatinib (BMS 354825)FDA Link
10/2015
1pyrvinium (Vankin)FDA Link
10/2015
1Tyrosine Kinase InhibitorsIBA
10/2015
1Casein Kinases (Casein Kinase)IBA
04/2015
1Trastuzumab (Herceptin)FDA Link
03/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2014
1villinIBA
06/2014
1PhosphoproteinsIBA
05/2013
1Zinc Finger NucleasesIBA
10/2012
1Sulfhydryl Compounds (Thiols)IBA
10/2010
1Arachidonic Acid (Vitamin F)IBA
10/2010
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
10/2010
1Casein Kinase IdeltaIBA
03/2007
1Threonine (L-Threonine)FDA Link
04/2005
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
04/2005
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
04/2005
1Biological ProductsIBA
04/2005
1Basic Helix-Loop-Helix Transcription FactorsIBA
04/2005
1Cyclosporine (Ciclosporin)FDA LinkGeneric
11/2002
13,4-dihydroxyphenylglycolIBA
11/2002
11,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterIBA
11/2002

Therapy/Procedure

6Therapeutics
01/2021 - 05/2015
1Drug Therapy (Chemotherapy)
01/2021
1Precision Medicine
11/2016